Scienceline Publications Journal of World's Poultry Research 2322-455X 11 2 2021 June A Comprehensive Review on Adenoviruses Infections in Fowl: Epidemiology, Forms, Diagnosis, and Control 151 167 http://jwpr.science-line.com/attachments/article/58/JWPR%2011(2)%20151-167,%202021.pdf EN Wafaa A. Abd El-Ghany Poultry Diseases Department, Faculty of Veterinary Medicine, Cairo University, 1211, Giza, Egypt Fowl Adeno Viruses (FAdVs) are non-enveloped and double-stranded DNA viruses. They include eight species (FAdVs A-E) and 12 serotypes (FAdVs-1 to -8a and -8b to -11). Strains of FAdVs have been widely distributed in different countries all over the world. Most avian species are susceptible to FAdVs infections. Vertical, horizontal, and mechanical infections and transmissions have been recorded in different forms of FAdVs infection. There are many forms of FAdVs infections according to the groups (including three groups) of the virus. Group 1 usually causes inclusion body hepatitis, hydropericardium syndrome, quail bronchitis, pancreatic erosions, gizzard erosion, cardiovascular, hematopoietic, and respiratory systems disorders. Group II is incriminated in diseases, such as turkey hemorrhagic enteritis, marble spleen disease in pheasants, and splenomegaly in chickens. In addition, group III is responsible for egg drop syndrome in laying chickens. Diagnosis of FAdVs infections is not based on the signs and lesions. However, microscopic detection of specific lesions and inclusion bodies may be suggestive. Diagnosis is mainly based on the conventional traditional isolation in embryonated eggs of different avian species as well as on tissue culture of avian origin. Molecular diagnostic techniques are now widely used for rapid and confirmative detection of FAdVs. The application of sanitary and hygienic measures in poultry farms is very important to prevent FAdVs outbreaks. However, different types of inactivated, living attenuated as well as recombinant vaccines have been developed and used in several countries to overcome different forms of FAdVs. Therefore, this review article deals with the FAdVs susceptibility and transmission, the etiological agent, forms of infections, and diagnosis as well as different methods of prevention and control. Egg drop syndrome Fowl adenoviruses Hydropericardium syndrome Inclusion body hepatitis Quail bronchitis Turkey hemorrhagic enteritis