Scienceline Publications Journal of World's Poultry Research 2322-455X 8 3 2018 September Effect of Lithium Toxicity in Broiler 59 65 http://jwpr.science-line.com/attachments/article/46/J%20World%20Poult%20Res%208(3)%2059-65,%202018.pdf EN Rokhsana Rasooli PhD student of Pharmacology, Faculty of Veterinary Medicine, University of Shiraz, Shiraz, Iran Iman Salamatian DVM, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran Maryam Aghazamani PhD student of Pharmacology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran Ahmad Oryan Department of Pathology, School of Veterinary Medicine, University of Shiraz, Shiraz, Iran Mahmood Salehi Department of Poultry Science, Faculty of Veterinary Medicine, Shahid Bahonar University of Kerman, Kerman, Iran Hadi Rohollahzadeh Resident of Poultry Science, Faculty of Veterinary Medicine, University of Shiraz, Shiraz, Ira Lithium concentration in surface and underground water, in some instances is higher than the standard level in places where lithium-rich brines and minerals occur, and in places where lithium batteries disposed of. This metal has numerous effects on human and other organisms, but there is no evidence about its effects on birds. For the first time we evaluated the effects of experimental lithium consumption in birds. The broiler chicks received daily 200 ppm lithium carbonate in their water, for 20 days and control group received water without lithium. At the end, blood samples collected for chemical analyses and the chickens were then euthanized and samples from brain, kidneys, gastrointestinal tract, heart and liver were collected for histopathological studies. Gross and microscopic lesions in organs were evaluated. Serum Glutamate Pyruvate Transaminase (SGPT), Serum Glutamate Oxaloacetate Transaminase (SGOT) and Uric acid also measured. The significant differences between experimental group and control group were seen. Lithium Toxicity Bird Histopathology Clinical pathology